Letterer-Siwe's syndrome; report of a case with unusual peripheral blood changes.

In 1933 Siwe laid down the criteria of the syndrome now called Letterer-Siwe disease, and in the literature before and after that date the different features are discussed and related to the reported cases. The following case illustrates in particular the peripheral blood changes which may occur in this condition, and a table is appended summarizing the clinical and pathological features of 18 cases beginning with Letterer's (1924) case and bringing the series up to date (1950) with the present case.